The BRICS Technology Transfer Center in China was proposed during the 2017 BRICS Conference on Technology Transfer and Innovation Cooperation and was written into the Durban Declaration and Programme of Action, the outcome document of the 2018 BRICS Ministerial Meeting on Science, Technology and Innovation.

In September 2018, the second meeting of the BRICS Working Group on Science, Technology, Innovation and Entrepreneurship Partnership was held in Kunming, Yunnan province in southwestern China. After the meeting, the BRICS Technology Transfer Center was unveiled by representatives of the five countries. So far, BRICS technology transfer meetings have been held in Kunming for six consecutive years.

The BRICS Technology Transfer Center online platform was launched in 2019. It has automatic translation functions in 17 languages including the languages spoken in BRICS countries, South Asian countries, and Southeast Asian countries.

The BRICS Technology Transfer Center has contributed to a series of international cooperation projects. A long-term mechanism for training and introducing international talents has been established.

The BRICS Technology Transfer Center has established cooperation mechanisms with 35 official technology transfer agencies in seven countries. Establishing cooperation mechanisms in medical health and intellectual property is under discussion.

The China-BRICS Science and Innovation Incubation Park for the New Era was opened in Xiamen, Fujian province in southeastern China, in December 2023.